British scientists have developed genetically modified chickens that are incapable of transmitting avian influenza virus to other chickens in a flock, an advance that could stop the spread of bird flu outbreaks. It would also reduce the risk of bird flu epidemics becoming new flu epidemics among humans. To produce the transgenic chickens, the scientists introduced a new gene that manufactures a "decoy" molecule that mimics a key control element of the flu virus, thus tricking the replication mechanism of the virus into recognizing the decoy instead of the viral genome. This process interrupts the replication cycle of the virus. The transgenic chickens who were infected with avian flu became sick, but did not transmit the infection to chickens kept in the same pen, researchers noted.
"Suppression of Avian Influenza Transmission in Genetically Modified Chickens", Science, January 13, 2011
Antioxidants like vitamins C and E have an unexpected negative side effect, according to Israeli researchers: they may cause fertility problems in females. Antioxidant supplements are widely available over the counter and are added to food, drink, and face cream, despite the fact that little is known about how they act in the body. Antioxidants eliminate cell-damaging molecules called reactive oxygen species produced naturally in the body and in large amounts at times of stress. But when researchers applied antioxidants to the ovaries of female mice, ovulation levels dropped dramatically: very few eggs were released from the ovaries to reach the site of fertilization, compared to those in untreated ovaries. The reason for the phenomenon? Ovulation relies on the “harmful” substances destroyed by antioxidants: reactive oxygen species.
"Reactive oxygen species are indispensable in ovulation", Proceedings of the National Academy Of Science, January 10, 2011
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Proceedings of the National Academy of Sciences, January 10, 2011
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