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Absorption Of BPA Increases With Continuous Exposure – Study

June 6, 2011: 09:48 AM EST
A U.S. study that tested long term dietary exposure to bisphenol A (BPA), a chemical used in the manufacture of polycarbonate plastic containers, including baby bottles and water bottles, found that BPA accumulates in the body faster than scientists previously thought. BPA has been found to be a disruptor of the endocrine system, but animal studies tested large single doses of BPA, finding them tolerable and relatively safe. This study in mice, however, found that the absorption and accumulation of BPA in the blood increased when the mice were given repeated doses as a dietary supplement, instead of one large dose. Researchers concluded that continuous exposure to BPA in the diet is “a better predictor of BPA concentrations in chronically exposed animals and humans.”
Paizlee T. Sieli, et al., "Comparison of Serum Bisphenol A Concentrations in Mice Exposed to Bisphenol A through the Diet versus Oral Bolus Exposure", Environmental Health Perspectives, June 06, 2011, © National Institute of Environmental Health Sciences (NIEHS)
Food Safety
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United States of America
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