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Higher Folic Acid Intake During Pregnancy Does Not Cause Childhood Atopic Diseases

June 20, 2011: 10:22 AM EST
A study revealed that folic acid supplementation and higher intracellular folic acid (ICF) levels during pregnancy are not associated with atopic diseases, such as asthma and wheeze, in childhood. Researchers conducted multivariable logistic and linear regression analyses of data gathered via the KOALA Birth Cohort Study. They also defined folic acid use as standalone and multivitamin supplements based on the period of use before and during pregnancy. Results of the study showed that increased ICF levels during pregnancy slightly decreased risk for developing asthma.
Fabienne J. H. Magdelijns, MSc, Monique Mommers, PhD, John Penders, PhD, Luc Smits, PhD, Carel Thijs, MD, PhD, "Folic Acid Use in Pregnancy and the Development of Atopy, Asthma, and Lung Function in Childhood", Pediatrics, June 20, 2011, © American Academy of Pediatrics
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