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Study Finds Human Exposure To Toxic Chemical BPA Is Higher Than Predicted

September 20, 2010: 11:54 AM EST

Contrary to the findings of earlier research, exposure to toxic bisphenol-A  (BPA) is much greater than previously thought, and comes from other sources besides oral ingestion, according to a U.S. study. The researchers provide evidence that women, female monkeys and female mice metabolize BPA in similar fashion, so animal studies are valid predictors. They call for more stringent federal rules on the use of the estrogen-like chemical found in many everyday products, including baby bottles and food-storage containers. The study argues that the available animal study data is sufficient: there is no need of more evidence of human harm before regulatory action is taken. “Our data raise grave concern that regulatory agencies have grossly underestimated current human exposure levels” because they relied on an earlier study whose conclusions were false.

Julia A. Taylor, et al., "Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human Exposure", Environmental Health Perspectives, September 20, 2010, © Ambra Publishing System
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